Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ Vancomycin HCl
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Antibiotic
Tocris Bioscience™ Cell Activation Cocktail 500X
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Cell activation cocktail
Tocris Bioscience™ AZD 2066
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mGlu5 antagonist; orally bioavailable and brain penetrant
Tocris Bioscience™ Ritonavir
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HIV-1 and HIV-2 protease inhibitor
Tocris Bioscience™ MK 386
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CAS: 158493-17-5 Molecular Formula: C28H49NO
| CAS | 158493-17-5 |
|---|---|
| Molecular Formula | C28H49NO |
Tocris Bioscience™ PF 05089771
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Potent and selective Nav1.7 channel blocker
| Target | Voltage-gated Sodium Channel Blockers |
|---|---|
| CAS | 1430806-04-4 |
| Purity | >98% |
| Chemical Name or Material | 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C18H12Cl2FN5O3S2.C7H8O3S |
| Formula Weight | 672.56 |
Tocris Bioscience™ Taxol
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CAS: 33069-62-4 Molecular Formula: C47H51NO14
| CAS | 33069-62-4 |
|---|---|
| Molecular Formula | C47H51NO14 |
Tocris Bioscience™ SC 19220
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CAS: 19395-87-0 Molecular Formula: C16H14ClN3O3
| CAS | 19395-87-0 |
|---|---|
| Molecular Formula | C16H14ClN3O3 |
Tocris Bioscience™ (-)-Cytisine
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CAS: 485-35-8 Molecular Formula: C11H14N2O
| CAS | 485-35-8 |
|---|---|
| Molecular Formula | C11H14N2O |
Tocris Bioscience™ PF 04620110
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Potent and selective DGAT-1 inhibitor; orally bioavailable
| CAS | 1109276-89-2 |
|---|---|
| Chemical Name or Material | trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]cyclohexaneacetic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C21H24N4O4 |
| Formula Weight | Observed MW: 396.44 |
| Assay Percent Range | >98% |
Tocris Bioscience™ BIRB 796
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High affinity and selective p38 kinase inhibitor
| Target | p38 Inhibitors |
|---|---|
| CAS | 285983-48-4 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
| Recommended Storage | Store at -20°C |
| Synonym | Doramapimod |
| Molecular Formula | C31H37N5O3 |
| Formula Weight | 527.66 |
Tocris Bioscience™ Serotonin hydrochloride
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CAS: 153-98-0 Molecular Formula: C10H13ClN2O
| CAS | 153-98-0 |
|---|---|
| Molecular Formula | C10H13ClN2O |
Tocris Bioscience™ VU 6001966
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Potent and selective negative allosteric modulator of mGlu2 receptors
Tocris Bioscience™ W146
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Potent and selective S1P1 receptor antagonist
Tocris Bioscience™ Tasquinimod
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Tasquinimod is a high affinity negative allosteric modulator of HDAC4 (Kd = 10 to 30 nM).